The Covaris Adaptive Focused Acoustics™ (AFA) process uses acoustic energy wave packets from a dish-shaped transducer to reproducibly shear DNA fragments to tight size distribution ranges. The Covaris technology enables controlled, quantitative and standardised sample preparation for various applications, including shearing DNA fragments for next generation sequencing library preparation.

The Covaris System is the only system that can successfully and reproducibly shear DNA in the size range of 100-5,000 bp+, eliminating the need for multiple shearing technologies. The process also maintains DNA integrity, as shearing is carried out under temperature-controlled conditions in a closed vessel, which eliminates the risk of cross-contamination.

Covaris support and resources, including applications, how the technology works, protocols, FAQs and publications, are provided at the Covaris website.

Instrument Booking

• Training is required prior to using the Covaris instrument
• Contact the Facility medicalgenomic@monash.edu for Covaris training
• Book Covaris training using our booking system ARIN